RXR Nuclear Receptor Agonists Promote Clearance of Alpha-Synuclein in Cellular Models
SPRING, Texas, Aug. 05, 2026 (GLOBE NEWSWIRE) -- Io Therapeutics, Inc., a privately held pharmaceutical company headquartered in Spring, Texas, announced today the presentation of new research demonstrating that IRX4204, the company’s phase II clinical stage highly selective RXR nuclear receptor agonist, promotes degradation of alpha-synuclein protein in human neural cells.
Global industrial production sentiment splits as Canada, India and South Korea strengthen while UK, Germany and China weaken, Permutable data shows
London, LONDON, Aug. 05, 2026 (GLOBE NEWSWIRE) -- Global industrial production sentiment is becoming increasingly divided, with resources, metals, electricity supply and investment-related activity strengthening while automotive manufacturing and demand-sensitive industries remain under pressure, according to new data from Permutable.
Google shakes up AI leadership. Demis Hassabis takes on broader research role, and Jeff Dean leaves.
Shane Anthony Sinclair/Getty Images for Cannes Lions
Google is shaking up its AI leadership, with some of the company's top experts in the field moving roles or leaving. Shares of the tech giant fell as much as 5% on the news.
I've been a Costco member for 15 years. Here are 7 items I always buy for my household of 2.
Stacy Boe Miller
Russian attack kills at least 17 in Kyiv as Ukraine hammers more Wildberries warehouses
An aerial view shows a massive column of smoke rising above Kyiv from a burning NOVUS supermarket chain warehouse following a Russian ballistic missile attack on the capital on August 5, 2026 in Kyiv, Ukraine.
SoftBank jumps 13% as Asia tech stocks track Wall Street AI rally
CANADA - 2025/08/07: In this photo illustration, the SoftBank Group (Soft Bank) logo is seen displayed on a smartphone screen. (Photo Illustration by Thomas Fuller/SOPA Images/LightRocket via Getty Images)
Sopa Images | Lightrocket | Getty Images
SpaceX and Nvidia are taking their relationship exclusive
Bloomberg/Getty Images
SpaceX says it's ready to be a one-chip supplier company.
On SpaceX's highly anticipated earnings call on Wednesday, CEO Elon Musk said his company was committed to buying graphics processing units from only one place.
The Grief Nobody Talks About When Your Career Stops Defining You
The Grief Nobody Talks About When Your Career Stops Defining You getty
You receive the severance package, announce your retirement, or sell the company you spent years building. You may still have a job, but people have stopped including you in decisions and responsibilities that once required your judgment are slowly being handed to someone else. Friends try to help. They suggest consulting, travel, volunteer work, or a long-overdue break. Their intentions are good, but their advice can miss the real loss. You are no longer sure where you fit, what people need from you, or how to describe yourself without referring to the position you held. What appears to be a career transition can feel a lot like grief.
UFC Noche: 10-Fight Card Announced, Date And Location
NEW YORK, NEW YORK - JULY 26: President and CEO of Ultimate Fighting Championship Dana White speaks at a press conference following fight night at Infosys Theater at Madison Square Garden on July 26, 2026 in New York City. (Photo by Evan Bernstein/Getty Images)
MLB Best Home Run Bets For August 5, 2026—Alvarez And Caglianone
Yordan Alvarez can add to his MLB lead in home runs with another homer today. Getty Images
The MLB best home run bets are mired in a genuinely frustrating funk, with 10 consecutive incorrect home run props. The long-shot nature of home run bets means losing streaks are part of the rollercoaster ride.